Salivary gland tumors:profiling and biomarker discovery
نویسنده
چکیده
The studies described in this thesis were carried out at the departments of Oral and Contents Chapter 1: General Introduction 9 Chapter 2: Variations in mucins and mucin-associated carbohydrate 25 antigens expression in mucoepidermoid carcinomas Chapter 3: High number of chromosomal copy number aberrations 43 inversely relates to t(11;19)(q21;p13) translocation status in Mucoepidermoid Carcinoma of the Salivary Glands Chapter 4: Human salivary microRNAs and their utility for 61 the detection of parotid salivary gland neoplasms Chapter 5: Discovery and pre-validation of salivary extracellular microRNA 79 biomarkers panel for the non-invasive detection of benign and malignant parotid gland tumors Chapter 6: The discovery of predictive salivary miRNAs as biomarkers for 97 salivary gland tumors via statistical machine learning Chapter 7: General summary and future aspects 115 Chapter 8: Algemene Samenvatting 125 Chapter 9: Dankwoord (Acknowledgements) 129
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